What are the risk factors for advanced sleep phase disorder (ASPD)?

As with DSPD, the etiology of ASPD is unknown. Studies suggest a contribution of physiologic (e.g., a shortened free-running period) and genetic (circadian clock gene polymorphism) factors.³⁰  

Autosomal-dominant inheritance of ASPD has been demonstrated in familial cases.^{31 32}

References

30. Toh KL, Jones CR, He Y, et al. An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome. Science. 2001;291:1040-1043

31. Reid KJ, Chang AM, Dubocovich ML, et al. Familial advanced sleep phase syndrome. Arch Neurol. 2001;58:1089-1094.

32.  Satoh K, Mishima K, Inoue Y, Ebisawa T, Shimizu T. Two pedigrees of familial advanced sleep phase syndrome in Japan. Sleep. 2003;26:416-417.